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稿件编号: L4124
稿件标题: 急性脑梗死患者血小板参数与脂蛋白(a)及CRP变化的研究
稿件作者: 王修石;
关键字词: 脑梗死;血小板;平均血小板体积;血小板分布宽度;脂蛋白(a);C-反应蛋白
文章摘要: 【摘要】 目的 对急性脑梗死患者血小板及其参数脂蛋白(a)和CRP指标检测结果进行分析,为早期诊断和治疗急性脑梗死提供参考依据。 方法 分别采用全自动血液分析仪(BC5500)和全自动生化分析仪(日立7600-010)测定491例急性脑梗死患者和40例健康对照的血小板及其参数和脂蛋白(a)和CRP指标。 结果 脑梗死患者组血小板及其参数、脂蛋白a和C-反应蛋白的测定:与健康对照组比较,PLT、PCT显减少,PDW、MPV、LP(a)和CRP明显升高,差异均有明显变化,都具有统计学意义(p<0.01)。结论 血小板数量及体积改变、Lp(a)和CRP的变化与急性脑梗死的发生,发展密切相关,监测它们的变化对脑梗死的预测和防治具有重要的临床意义。
中图分类号: R
杂志名称: 检验医学与临床
文章刊期: 2011年08卷04期
文章栏目: 论著
稿件标题(英文): Platelet parameters in patients with acute cerebral infarction and lipoprotein (a), CRP Changes
稿件作者(英文): wangxiushi;
关键字词(英文): Cerebral infarction;Platelet;Mean platelet volume;Platelet distribution width;Lipoprotein(a);C-react
文章摘要(英文): 【Abstract】 Objective  Patients with acute cerebral infarction and its parameters of platelet lipoprotein (a) and CRP analysis of test results indicators for the early diagnosis and treatment of acute cerebral infarction to provide reference. Methods Using automated Hematology Analyzer (BC5500) and automatic biochemical Analyzer (Hitachi 7600-010) determination of 491 cases of acute cerebral infarction and 40 cases of health control of platelet and its parameters and lipoprotein (a) and CRP indicators. Results Cerebral infarction and platelet parameters, lipoprotein a, and C-reactive protein: comparison with healthy control group, PLT, PCT significantly decreased, PDW, MPV, LP (a) and CRP increased significantly, the differences were significant changes are statistically significant (p <0.01). Conclusion Platelet count and volume change, Lp (a) and the CRP and the incidence of acute cerebral infarction, closely related to the development, monitoring of changes on cerebral infarction of forecast and prevention have important clinical implications.
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