| 稿件编号： | L3818 |
| 稿件标题： | N末端脑钠肽在急性心肌梗死中的应用 |
| 稿件作者： | 熊大迁; |
| 关键字词： | N末端脑钠肽，急性心肌梗死，主要心脏不良事件 |
| 文章摘要： | 摘 要 目的 评价N末端脑钠肽（NT-proBNP）在急性心肌梗死（AMI）发生后的应用价值。方法 采用双向侧流免疫法测定AMI患者入院后24h、48h内NT-proBNP的血清水平。结果 AMI患者入院后24h、48h血清NT-proBNP水平高于对照组（968.4±38.93pg/ml，1023.5±205.3pg/ml；VS ＜250。P＜0.01）。高水平的NT-proBNP AMI患者(1720.5±650.7pg/ml)发生主要心脏不良事件（MACE）的危险性高于低水平（350.6±78.5pg/ml）的AMI患者(P＜0.05)。结论 AMI患者血清具有较高的NT-proBNP水平，其浓度的高低对AMI的治疗、危险分层和预后具有重要的意义。 |
| 中图分类号： | R |
| 杂志名称： | 检验医学与临床 |
| 文章刊期： | 2011年08卷04期 |
| 文章栏目： | 论著 |
| 稿件标题（英文）： | Application of Serum NT-proBNP for The Diagnosis of Acute Myocardial Infarction |
| 稿件作者（英文）： | xiongdaqian; |
| 关键字词（英文）： | NT-proBNP, acute myocardial infarction ,main adverse cardiac events |
| 文章摘要（英文）： | Abstract：Objective To investigate the value of NT-proBNP in the acute myo- cardial infarction(AMI)．Method The serum concentration of NT-proBNP in patients with AMI were measured within 24h and 48h after admission by cross immunoelectrophoresis methods. Results Serum NT-proBNP concentration in patients with AM1 within 24h and 48h after admission was significantly higher than that in healthy subjects (968.4±38.93pg/ml，1023.5±205.3pg/ml；VS ＜250.P＜0.01)。The higher serum levels of NT-proBNP in AMI patients (1720.5±650.7pg/ml) with main adverse cardiac events(MACE) was significantly higher than that the lower levels of NT-proBNP in AMI patients（350.6±78.5pg/ml）(p＜0.05） Conclusion Serum NT-proBNP concentration in patients with AMI has higher levels. Study of the concentration of Serum NT-proBNP is important in the diagnosis, treatment and prognosis of AMI. |
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